Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis

Entities Mentioned

• Heidelberg Engineering

1. BackgroundStudying axonal loss in the retina is a promising biomarker for multiple sclerosis (MS). Our aim was to compare optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) techniques to measure the thickness of the retinal nerve fiber layer (RNFL) in patients with MS, and to explore the relationship between changes in the RNFL thickness with physical and cognitive disability. We studied 52 patients with MS and 18 proportionally matched controls by performing neurological examination, neuropsychological evaluation using the Brief Repetitive Battery-Neuropsychology and RNFL thickness measurement using OCT and HRT.ResultsWe found that both OCT and HRT could define a reduction ... (Read Full Article)
   
   

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