1. Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially treat these lesions many invasive and non-invasive imaging modalities are undergoing evaluation. While techniques such as intravascular ultrasound (IVUS), especially combined with radiofrequency analysis, have been significant developments providing valuable information in ... (Read Full Article)

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