1. Purpose: To utilize time-domain optical coherence tomography (OCT) to measure changes in the crystalline lens with age and accommodation.Methods: A cross-sectional study of pre-presbyopic and presbyopic subjects was conducted. Amplitude of accommodation was measured with the push-up test. Objective accommodation was measured with the Grand Seiko auto-refractor and a Badal lens system. Lens thickness was measured with the Zeiss Visante OCT and an internal optometer. The data were analysed using correlation coefficients, linear regression, and by calculating the average change in lens thickness per diopter change in objective accommodation.Results: Twenty-two subjects between the ages of 36 and 50 ... (Read Full Article)

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