1. Optical Coherence Tomography–Enhanced Microlaryngoscopy: Preliminary Report of a Noncontact Optical Coherence Tomography System Integrated With a Surgical Microscope

    annals.com (Aug 15 2008) Endoscopy , Microscopy Explore Article

    Objectives: Optical coherence tomography (OCT) is a new imaging modality that uses near-infrared light to produce cross-sectional images of tissue with a resolution approaching that of light microscopy. We have previously reported use of OCT imaging of the vocal folds (VFs) during direct laryngoscopy with a probe held in contact or near-contact with the VFs. This aim of this study was to develop and evaluate a novel OCT system integrated ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   University of California at Irvine   Shuguang Guo

  2. Optical Coherence Tomography of the Newborn Airway

    annals.com (Jun 21 2008) Bronchoscopy Explore Article

    Objectives: Acquired subglottic stenosis in a newborn is often associated with prolonged endotracheal intubation. This condition is generally diagnosed during operative endoscopy after airway injury has occurred. Unfortunately, endoscopy is unable to characterize the submucosal changes observed in such airway injuries. Other modalities, such as magnetic resonance imaging, computed tomography, and ultrasound, do not possess the necessary level of resolution to differentiate scar, neocartilage, and edema. Optical coherence tomography (OCT) ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   University of California at Irvine   Shuguang Guo

  3. Optical Coherence Tomography of the Cochlea in the Porcine Model.

    The Laryngoscope (May 15 2008) Explore Article

    Abstract: Objectives/Hypothesis: To demonstrate the feasibility of optical coherence tomography in microstructural imaging of the porcine cochlea. Study Design: Ex vivo, porcine model. Methods: Optical coherence tomographic images of the porcine cochlea were obtained by thinning the bone from the basal turn of the cochlea leaving the endosteum intact. The images were compared with the corresponding histological sections. Results: In the areas of thinned bone, images were obtained of the ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen

  4. Optical coherence tomography of the larynx in the awake patient

    ScienceDirect (Mar 25 2008) Endoscopy Explore Article

    Objective To demonstrate the feasibility of performing optical coherence tomography of the human larynx on the awake patient with a novel flexible fiberoptic delivery system. Study Design Prospective clinical trial. Subjects and Methods Imaging was performed in 17 awake patients. A flexible optical coherence tomography probe was inserted through the nose and placed in near or gentle contact with laryngeal tissues under direct endoscopic visualization. Results Images were successfully obtained ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   Shuguang Guo   University of California at Irvine

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