1. In Vivo Optical Coherence Tomography of the Human Oral Cavity and Oropharynx

    archotol.ama-assn.org (Nov 24 2008) Explore Article

    Optical coherence tomography (OCT) is an evolving imaging modality that combines interferometry with low-coherence light to produce high-resolution tissue imaging. Cross-sectional in vivo images were obtained using an OCT device consisting of a Michelson interferometer, 1.3-µm broadband light source, and a handheld fiberoptic imaging probe. Image pixel resolution approached 10 µm. The mucosa of the oral cavity and oropharynx were examined in 41 patients during operative endoscopy. Optical coherence tomographic ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   University of California at Irvine   Shuguang Guo

  2. Optical Coherence Tomography–Enhanced Microlaryngoscopy: Preliminary Report of a Noncontact Optical Coherence Tomography System Integrated With a Surgical Microscope

    annals.com (Aug 15 2008) Endoscopy , Microscopy Explore Article

    Objectives: Optical coherence tomography (OCT) is a new imaging modality that uses near-infrared light to produce cross-sectional images of tissue with a resolution approaching that of light microscopy. We have previously reported use of OCT imaging of the vocal folds (VFs) during direct laryngoscopy with a probe held in contact or near-contact with the VFs. This aim of this study was to develop and evaluate a novel OCT system integrated ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   University of California at Irvine   Shuguang Guo

  3. Optical Coherence Tomography of the Newborn Airway

    annals.com (Jun 21 2008) Bronchoscopy Explore Article

    Objectives: Acquired subglottic stenosis in a newborn is often associated with prolonged endotracheal intubation. This condition is generally diagnosed during operative endoscopy after airway injury has occurred. Unfortunately, endoscopy is unable to characterize the submucosal changes observed in such airway injuries. Other modalities, such as magnetic resonance imaging, computed tomography, and ultrasound, do not possess the necessary level of resolution to differentiate scar, neocartilage, and edema. Optical coherence tomography (OCT) ... (Read Full Article)

    Comment on Article Mentions:   Zhongping Chen   University of California at Irvine   Shuguang Guo

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