1. High-resolution imaging diagnosis and staging of bladder cancer: comparison between optical coherence tomography and high-frequency ultrasound

    SPIE Digital Library (Sep 12 2008) Endoscopy Explore Article

    Zhijia Yuan, Zhenguo Wang, Rubin Pan et al. A comparative study between 1.3-[mu]m optical coherence tomography (OCT) and 40-MHz high-frequency ultrasound (HFUS) is presented to enhance imaging of bladder cancers ex vivo. A standard rat bladder cancer model in which transitional cell carcinoma (TCC) was induced by intravesical instillation of ... [J. Biomed. Opt. 13, 054007 (2008)] published Fri Sep 12, 2008. (Read Full Article)

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  2. Optical coherence Doppler tomography quantifies laser speckle contrast imaging for blood flow imaging in the rat cerebral cortex

    opticsinfobase.org (May 14 2008) Explore Article

    Zhongchi Luo, Zhenguo Wang, Zhijia Yuan, Congwu Du, Yingtian PanA dual-imaging modality is demonstrated for high-resolution quantitative imaging of local cerebral blood flow in the rat cortex by combining simultaneous spectral-domain Doppler optical coherence tomography (SDOCT) and full-field laser speckle contrast imaging (LSCI). Preliminary studies in tissue ... [Opt. Lett. 33, 1156-1158 (2008)] (Read Full Article)

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  3. Assessment of Dermal Wound Repair after Collagen Implantation with Optical Coherence Tomography

    Mary Ann Liebert, Inc. (May 6 2008) Dermatology Explore Article

    We present an animal study to examine the utility and potential limitations of optical coherence tomography (OCT) for noninvasive evaluation of biomaterial scaffold–assisted wound healing. The transverse and axial resolutions of the OCT system at the wavelength of 1.3 μm were 12 and 10 μm, respectively. A murine full-thickness transcutaneous wound model was employed, in which a 10 mm full-thickness wound was created on the back of each male Balb/cJ ... (Read Full Article)

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  4. Optical Coherence Tomography: A Noninvasive Method to Assess Wound Reepithelialization

    Blackwell Synergy (Jan 8 2008) Explore Article

    Background Accurate assessment of wound healing may require invasive tissue biopsies, limiting its clinical usefulness in humans. Optical coherence tomography (OCT) is a novel, high-resolution method using light reflection to obtain noninvasive cross sectional imaging of biological tissues. ObjectivesTo evaluate the utility of OCT for assessing wound reepithelialization in a porcine model. MethodsThe authors conducted an animal study with two domestic pigs. Excisional cutaneous wounds were created over the ventral ... (Read Full Article)

    Comment on Article Mentions:   Yingtian Pan

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