1. Visualization of Sub-retinal Pigment Epithelium Morphologies of Exudative Macular Diseases by High-Penetration Optical Coherence Tomography

    Explore Article iovs.org (Jan 4 2009) Ophthalmology

    PURPOSE. To evaluate the clinical significance of the newly developed long-wavelength probe optical coherence tomography (LP-OCT) for the diagnosis of exudative macular diseases. METHODS. Fourteen eyes of 13 participants were prospectively enrolled in the study. There were seven type I and five type II choroidal neovascularization (CNV) cases associated with age-related macular degeneration and idiopathic neovascularization and one case of polypoidal choroidal vasculopathy (PCV). A custom-built LP-OCT based on swept-source ... (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   Masahiro Yamanari

  2. Full-range, high-speed, high-resolution 1 mu m spectral-domain optical coherence tomography with BM-scan method for the human posterior eye imaging

    Explore Article SPIE Digital Library (Dec 30 2008) Ophthalmology

    High-speed, high-resolution full-range 1 [mu]m spectral-domain optical coherence tomography has been demonstrated. The axial resolution of 7 [mu]m and the depth range of 2.6 mm in tissue are achieved with the line rate of 46,900 Hz. The sensitivity of 98 dB is obtained with full-range imaging. These ... [Proc. SPIE 7139, 713914 (2008)] published Tue Dec 30, 2008. (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   University of Tsukuba

  3. Optical coherence tomography for the investigation of posterior and anterior eye segments

    Explore Article SPIE Digital Library (Dec 30 2008) Ophthalmology

    The applications of three-dimensional Fourier domain optical coherence tomography (FD-OCT) to ophthalmology are demonstrated. The fundamentals of two types of FD-OCT, i.e., spectral domain OCT (SD-OCT) and swept source OCT (SS-OCT) are described. The 3D investigation of age-related macular degenerat ... [Proc. SPIE 7139, 71390Y (2008)] published Tue Dec 30, 2008. (Read Full Article)

    Comment on Article Mentions:   Yoshiaki Yasuno   University of Tsukuba

  4. Comparison of Spectral Domain Optical Coherence Tomography and Color Photographic Imaging of the Optic Nerve Head in Management of Glaucoma

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Sep 10 2008) Ophthalmology

    BACKGROUND AND OBJECTIVE Spectral domain optical coherence tomography (SD-OCT) allows three-dimensional imaging of the optic disc. The objective of this study was to compare optic disc and cup margins between fundus photographs and SD-OCT. PATIENTS AND METHODS Eighteen eyes with glaucoma were examined by a custom-built SD-OCT. OCT fundus images were used to register fundus photographs and SD-OCT volume. RESULTS Disc margins on fundus photographs corresponded to termination of the ... (Read Full Article)

    Comment on Article Mentions:   Topcon Medical Systems   Yoshiaki Yasuno   Masahiro Yamanari

  5. Imaging Polarimetry in Age-Related Macular Degeneration

    Explore Article iovs.org (May 29 2008) Ophthalmology

    purpose. To evaluate the birefringence properties of eyes with age-related macular degeneration (AMD). To compare the information from two techniques—scanning laser polarimetry (GDx) and polarization-sensitive spectral-domain optical coherence tomography (OCT)—and investigate how they complement each other. methods. The authors prospectively examined the eyes of two healthy subjects and 13 patients with exudative AMD. Using scanning laser polarimetry, they computed phase-retardation maps, average reflectance images, and depolarized light images. To obtain ... (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   Masahiro Yamanari

  6. Full-range, high-speed, high-resolution 1μm spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye

    Explore Article opticsinfobase.org (May 23 2008) Ophthalmology , Broadband Sources

    Shuichi Makita, Tapio Fabritius, Yoshiaki Yasuno. An alternative optical coherence tomography (OCT) to clinical ophthalmic 830 nm spectral-domain OCTs (SD-OCT) is demonstrated. An axial resolution of 7.4 μm, ranging depth of 4.2 mm in tissue, sensitivity of 98.5 dB, and detection speed of 38,300 axial scans/s have been achieved. These are ... [Opt. Express 16, 8406-8420 (2008)] (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   University of Tsukuba

  7. Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation

    Explore Article opticsinfobase.org (Apr 11 2008) Tunable Sources

    Masahiro Yamanari, Shuichi Makita, Yoshiaki Yasuno We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a frequency swept laser centered at 1.31 μm with a scanning rate of 20 kHz. The incident polarization is modulated by a ... [Opt. Express 16, 5892-5906 (2008)] (Read Full Article)

    Comment on Article Mentions:   Yoshiaki Yasuno   Shuichi Makita   Masahiro Yamanari

  8. Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography

    Explore Article opticsinfobase.org (Apr 10 2008) Ophthalmology

    Shuichi Makita, Tapio Fabritius, Yoshiaki Yasuno. Retinal blood flow quantification by retinal vessel segmentation with Doppler optical coherence angiography is presented. Vessel diameter, orientation, and position are determined in an en face vessel image and two representative cross-sectional flow images of the vessel. Absolute blood flow ... [Opt. Lett. 33, 836-838 (2008)] (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   University of Tsukuba

  9. Polarization-sensitive swept-source optical coherence tomography with continuous polarization modulation

    Explore Article SPIE Digital Library (Feb 18 2008) Tunable Sources

    Masahiro Yamanari, Shuichi Makita, Toyohiko Yatagai et al. We present fiber-based polarization-sensitive swept-source optical coherence tomography (PS-SS-OCT) with continuous polarization modulation. The light source is a high-speed wavelength sweeping source with 1.3 um center wavelength and 20 kHz sweeping frequency. A resonant electro-optic modulator mod ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68471J (2008)] published Mon Feb 18, 2008. (Read Full Article)

    Comment on Article Mentions:   Masahiro Yamanari   Shuichi Makita   Yoshiaki Yasuno

  10. Retinal blood flow measurement by using optical coherence tomography

    Explore Article SPIE Digital Library (Feb 18 2008) Ophthalmology

    Shuichi Makita, Tapio Fabritius, Masahiro Miura et al. Quantification of the three-dimensional (3D) retinal vessel structure and blood flow is demonstrated. 3D blood flow distribution is obtained by Doppler optical coherence angiography (D-OCA). Vessel parameters, i.e. diameter, orientation, and position, are determined in an en face vessel image. The D ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68470J (2008)] published Mon Feb 18, 2008. (Read Full Article)

    Comment on Article Mentions:   Shuichi Makita   Yoshiaki Yasuno   University of Tsukuba

  11. High-penetration imaging of retinal and choroidal pathologies by 1 mu m swept-source OCT and optical coherence angiography

    Explore Article SPIE Digital Library (Feb 11 2008) Ophthalmology

    Yoshiaki Yasuno, Masahiro Miura, Fumiki Okamoto et al. Two pathologic cases are evaluated by high-penetration optical coherence tomography (HP-OCT) to demonstrate its clinical significance. The HP-OCT is based on a swept-source OCT (SS-OCT) technology with a probe wavelength of 1.06 [mu]m. The depth resolution is 10.4 [mu]m in tissue, and the measuremen ... [Proc. SPIE Int. Soc. Opt. Eng. 6844, 68441H (2008)] published Mon Feb 11, 2008. (Read Full Article)

    Comment on Article Mentions:   Yoshiaki Yasuno   University of Tsukuba

  12. Imaging the anterior eye segment by polarization-sensitive spectral-domain and swept-source optical coherence tomography

    Explore Article SPIE Digital Library (Feb 11 2008) Ophthalmology

    Masahiro Miura, Masahiro Yamanari, Toyohiko Yatagai et al. Polarization-sensitive optical coherence tomography (PS-OCT) has been developed to measure the birefringent properties of the human eye. In the retina, retinal nerve fiber layer and retinal pigment epitherial layer have the characteristic birefringent properties. In addition to such normal tissue, a ... [Proc. SPIE Int. Soc. Opt. Eng. 6844, 68441C (2008)] published Mon Feb 11, 2008. (Read Full Article)

    Comment on Article Mentions:   Masahiro Yamanari   Yoshiaki Yasuno   University of Tsukuba

  13. The evaluation of the photoaging of the human skin by three-dimensional polarization sensitive spectral domain optical coherence tomography

    Explore Article SPIE Digital Library (Feb 8 2008) Dermatology

    Arata Miyazawa, Shingo Sakai, Masayuki Matsumoto et al. Noninvasive evaluation of dermal degeneration is important for a diagnosis of photoaging. Polarization sensitive optical coherence tomography (PS-OCT) can measure the distribution of phase retardation caused by birefringence property of collagen. The PS-OCT has been reported as the technology of in ... [Proc. SPIE Int. Soc. Opt. Eng. 6842, 684207 (2008)] published Fri Feb 8, 2008. (Read Full Article)

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