Articles from Desmond C. Adler

1-7 of 7
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Application: Bronchoscopy, Cardiology, Dentistry, Dermatology, Endoscopy, Glucose, Microscopy, Non-Medical, Ophthalmology
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  1. Ultrahigh-Speed Optical Coherence Tomography for Three-Dimensional and En Face Imaging of the Retina and Optic Nerve Head

    iovs.org (Oct 28 2008) Ophthalmology Explore Article

    Ultrahigh-speed swept-source optical coherence tomography (OCT) imaging of the retina and optic nerve is demonstrated at 249,000 axial scans per second and 1060 nm, while methods for en face visualization of the retina, choroid, and lamina cribrosa are investigated. (Read Full Article)

    Comment on Article Mentions:   Desmond C. Adler   University of Pittsburgh   Massachusetts Institute of Technology

  2. Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation

    opticsinfobase.org (Oct 28 2008) Explore Article

    Benjamin R. Biedermann, Wolfgang Wieser, Christoph M. Eigenwillig, Gesa Palte, Desmond C. Adler, Vivek J. Srinivasan, James G. Fujimoto, Robert Huber We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a k-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, ... [Opt. Lett. 33, 2556-2558 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Desmond C. Adler   Massachusetts Institute of Technology

  3. Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography.

    NCBI HomePage (Jun 11 2008) Explore Article

    The detection of a gold nanoparticle contrast agent is demonstrated using a photothermal modulation technique and phase sensitive optical coherence tomography (OCT). A focused beam from a laser diode at 808 nm is modulated at frequencies of 500 Hz-60 kHz while irradiating a solution containing nanoshells. Because the nanoshells are designed to have a high absorption coefficient at 808 nm, the laser beam induces small-scale localized temperature oscillations at the ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Desmond C. Adler

  4. Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography

    opticsinfobase.org (Mar 17 2008) Explore Article

    Desmond C. Adler, Shu-Wei Huang, Robert Huber, James G. Fujimoto The detection of a gold nanoparticle contrast agent is demonstrated using a photothermal modulation technique and phase sensitive optical coherence tomography (OCT). A focused beam from a laser diode at 808 nm is modulated at frequencies of 500 Hz – 60 kHz while irradiating a solution ... [Opt. Express 16, 4376-4393 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Robert Huber   Desmond C. Adler

  5. Three-dimensional endomicroscopy using optical coherence tomography

    Nature Publishing Group (Feb 26 2008) Endoscopy Explore Article

    Optical coherence tomography enables micrometre-scale, subsurface imaging of biological tissue by measuring the magnitude and echo time delay of backscattered light. Endoscopic optical coherence tomography imaging inside the body can be performed using fibre-optic probes. To perform three-dimensional optical coherence tomography endomicroscopy with ultrahigh volumetric resolution, however, requires extremely high imaging speeds. Here we report advances in optical coherence tomography technology using a Fourier-domain mode-locked frequency-swept laser as the light ... (Read Full Article)

    Comment on Article Mentions:   LightLab Imaging   Massachusetts Institute of Technology   James G. Fujimoto

  6. In vivo endomicroscopy using three-dimensional optical coherence tomography and Fourier domain mode locked lasers

    SPIE Digital Library (Feb 19 2008) Endoscopy Explore Article

    Desmond C. Adler, Yu Chen, Robert Huber et al. We report an endoscopic optical coherence tomography (OCT) system based on a Fourier Domain Mode Locked (FDML) laser, a novel data acquisition (DAQ) system with optical frequency clocking, and a high-speed spiralscanning fiber probe. The system is capable of acquiring three-dimensional (3D) in vivo ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684708 (2008)] published Tue Feb 19, 2008. (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   Robert Huber   Desmond C. Adler

  7. Comparison of three-dimensional optical coherence tomography and high resolution photography for art conservation studies

    opticsinfobase.org (Nov 16 2007) Non-Medical Explore Article

    Desmond C. Adler, Jens Stenger, Iwona Gorczynska, Henry Lie, Teri Hensick, Ron Spronk, Stephan Wolohojian, Narayan Khandekar, James Y. Jiang, Scott Barry, Alex E. Cable, Robert Huber, James G. Fujimoto. Gold punchwork and underdrawing in Renaissance panel paintings are analyzed using both three-dimensional swept source / Fourier domain optical coherence tomography (3D-OCT) and high resolution digital photography. 3D-OCT can generate en face images with micrometer-scale resolutions at arbitrary ... [Opt. ... (Read Full Article)

    Comment on Article Mentions:   Desmond C. Adler   James G. Fujimoto   Alex Cable

1-7 of 7
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