Articles from Robert Huber

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Application: Art, Bronchoscopy, Cardiology, Dentistry, Dermatology, Developmental Biology, Endoscopy, Glucose, Gynecology, Microscopy, NDE/NDT, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Urology
Miscellaneous: Acquisition, Clinical Trials, Funding, Jobs & Studentships, Partnership, Patents, Textbooks
Technology: Broadband Sources, Probes, Propagation, Tunable Sources

  1. Raman-pumped Fourier-domain mode-locked laser: analysis of operation and application for optical coherence tomography

    Explore Article opticsinfobase.org (Nov 20 2008) Ophthalmology

    We demonstrate a Raman-pumped Fourier-domain mode-locked (FDML) fiber laser and optical coherence tomography imaging with this source. The wavelength sweep range of only 30 nm centered around 1550 nm results in limited axial resolution, hence a nonbiological sample is imaged. An output power of 1.9 ... [Opt. Lett. 33, 2815-2817 (2008)] (Read Full Article)

    Comment on Article Mentions:   Robert Huber

  2. Ultrahigh-Speed Optical Coherence Tomography for Three-Dimensional and En Face Imaging of the Retina and Optic Nerve Head

    Explore Article iovs.org (Oct 28 2008) Ophthalmology

    Ultrahigh-speed swept-source optical coherence tomography (OCT) imaging of the retina and optic nerve is demonstrated at 249,000 axial scans per second and 1060 nm, while methods for en face visualization of the retina, choroid, and lamina cribrosa are investigated. (Read Full Article)

    Comment on Article Mentions:   Desmond C. Adler   University of Pittsburgh   Massachusetts Institute of Technology

  3. Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation

    Explore Article opticsinfobase.org (Oct 28 2008) Tunable Sources

    Benjamin R. Biedermann, Wolfgang Wieser, Christoph M. Eigenwillig, Gesa Palte, Desmond C. Adler, Vivek J. Srinivasan, James G. Fujimoto, Robert Huber We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a k-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, ... [Opt. Lett. 33, 2556-2558 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Desmond C. Adler   Massachusetts Institute of Technology

  4. Mode locking methods and apparatus

    Explore Article PatFT » Page 1 of 1 (Aug 19 2008) Patents , Tunable Sources

    FIELD OF THE INVENTIONT he invention relates generally to the field of wave generation. In particular, the invention relates to Fourier Domain Mode Locking (FDML) and applications thereof. BACKGROUND OF THE INVENTIONIn many industries and technical areas of research, various systems and devices are used to obtain precise measurements or imaging. In conjunction with the need for precision, there is also a demand for high speed data collection. To satisfythese ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Robert Huber

  5. Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography.

    Explore Article NCBI HomePage (Jun 11 2008)

    The detection of a gold nanoparticle contrast agent is demonstrated using a photothermal modulation technique and phase sensitive optical coherence tomography (OCT). A focused beam from a laser diode at 808 nm is modulated at frequencies of 500 Hz-60 kHz while irradiating a solution containing nanoshells. Because the nanoshells are designed to have a high absorption coefficient at 808 nm, the laser beam induces small-scale localized temperature oscillations at the ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Desmond C. Adler

  6. K-space linear Fourier domain mode locked laser and applications for optical coherence tomography

    Explore Article opticsinfobase.org (Jun 3 2008) Tunable Sources

    Christoph M. Eigenwillig, Benjamin R. Biedermann, Gesa Palte, Robert HuberWe report on a Fourier Domain Mode Locked (FDML) wavelength swept laser source with a highly linear time-frequency sweep characteristic and demonstrate OCT imaging without k-space resampling prior to Fourier transformation. A detailed theoretical framework is provided and different strategies ... [Opt. Express 16, 8916-8937 (2008)] (Read Full Article)

    Comment on Article Mentions:   Robert Huber

  7. Photothermal detection of gold nanoparticles using phase-sensitive optical coherence tomography

    Explore Article opticsinfobase.org (Mar 17 2008)

    Desmond C. Adler, Shu-Wei Huang, Robert Huber, James G. Fujimoto The detection of a gold nanoparticle contrast agent is demonstrated using a photothermal modulation technique and phase sensitive optical coherence tomography (OCT). A focused beam from a laser diode at 808 nm is modulated at frequencies of 500 Hz – 60 kHz while irradiating a solution ... [Opt. Express 16, 4376-4393 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Robert Huber   Desmond C. Adler

  8. Improved spectral optical coherence tomography using optical frequency comb

    Explore Article opticsinfobase.org (Mar 12 2008)

    Tomasz Bajraszewski, Maciej Wojtkowski, Maciej Szkulmowski, Anna Szkulmowska, Robert Huber, Andrzej Kowalczyk. We identify and analyze factors influencing sensitivity drop-off in Spectral OCT and propose a system employing an Optical Frequency Comb (OFC) to verify this analysis. Spectral Optical Coherence Tomography using a method based on an optical frequency comb is demonstrated. Since the spectrum ... [Opt. Express 16, 4163-4176 (2008)] (Read Full Article)

    Comment on Article Mentions:   Maciej Wojtkowski   Robert Huber   Tomasz Bajraszewski

  9. Three-dimensional endomicroscopy using optical coherence tomography

    Explore Article Nature Publishing Group (Feb 26 2008) Endoscopy

    Optical coherence tomography enables micrometre-scale, subsurface imaging of biological tissue by measuring the magnitude and echo time delay of backscattered light. Endoscopic optical coherence tomography imaging inside the body can be performed using fibre-optic probes. To perform three-dimensional optical coherence tomography endomicroscopy with ultrahigh volumetric resolution, however, requires extremely high imaging speeds. Here we report advances in optical coherence tomography technology using a Fourier-domain mode-locked frequency-swept laser as the light ... (Read Full Article)

    Comment on Article Mentions:   LightLab Imaging   Massachusetts Institute of Technology   James G. Fujimoto

  10. In vivo endomicroscopy using three-dimensional optical coherence tomography and Fourier domain mode locked lasers

    Explore Article SPIE Digital Library (Feb 19 2008) Endoscopy

    Desmond C. Adler, Yu Chen, Robert Huber et al. We report an endoscopic optical coherence tomography (OCT) system based on a Fourier Domain Mode Locked (FDML) laser, a novel data acquisition (DAQ) system with optical frequency clocking, and a high-speed spiralscanning fiber probe. The system is capable of acquiring three-dimensional (3D) in vivo ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684708 (2008)] published Tue Feb 19, 2008. (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   Robert Huber   Desmond C. Adler

  11. High-resolution optical coherence tomography imaging of the living kidney.

    Explore Article NCBI HomePage (Feb 13 2008)

    Related Articles High-resolution optical coherence tomography imaging of the living kidney. Lab Invest. 2008 Feb 11; Authors: Andrews PM, Chen Y, Onozato ML, Huang SW, Adler DC, Huber RA, Jiang J, Barry SE, Cable AE, Fujimoto JG Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can provide non-invasive, cross-sectional, high-resolution images of tissue morphology in situ and in real-time. In the present series of studies, we used ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Thorlabs

  12. Comparison of three-dimensional optical coherence tomography and high resolution photography for art conservation studies

    Explore Article opticsinfobase.org (Nov 16 2007) Art

    Desmond C. Adler, Jens Stenger, Iwona Gorczynska, Henry Lie, Teri Hensick, Ron Spronk, Stephan Wolohojian, Narayan Khandekar, James Y. Jiang, Scott Barry, Alex E. Cable, Robert Huber, James G. Fujimoto. Gold punchwork and underdrawing in Renaissance panel paintings are analyzed using both three-dimensional swept source / Fourier domain optical coherence tomography (3D-OCT) and high resolution digital photography. 3D-OCT can generate en face images with micrometer-scale resolutions at arbitrary ... [Opt. ... (Read Full Article)

    Comment on Article Mentions:   Desmond C. Adler   James G. Fujimoto   Alex Cable

  13. High speed engine gas thermometry by Fourier-domain mode-locked laser absorption spectroscopy

    Explore Article opticsinfobase.org (Nov 7 2007)

    Laura A. Kranendonk, Xinliang An, Andrew W. Caswell, Randy E. Herold, Scott T. Sanders, Robert Huber, James G. Fujimoto, Yasuhiro Okura, Yasuhiro UrataWe present a novel method for low noise, high-speed, real-time spectroscopy to monitor molecular absorption spectra. The system is based on a rapidly swept, narrowband CW Fourier-domain mode-locked (FDML) laser source for spectral encoding in time and an optically time-multiplexed split-pulse data ... [Opt. Express 15, 15115-15128 (2007)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Massachusetts Institute of Technology   Robert Huber

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