Categories: Bronchoscopy, Cardiology, Dentistry, Dermatology, Endoscopy, Glucose, Microscopy, Non-Medical, Ophthalmology, Acquisition, Funding, Jobs & Studentships, Partnership, Patents
In vivo burn imaging using Mueller optical coherence tomography
opticsinfobase.org (Jun 26 2008)
Dermatology
Miloš Todorovic, Shuliang Jiao, Jun Ai, David Pereda-Cubián, George Stoica, Lihong V. Wang. We report on the use of a high-speed, fiber-based Mueller-matrix optical coherence tomography system with continuous source-polarization modulation for in vivo burn depth evaluation and healing monitoring. A homemade hand-held probe with integrated optical scanning and beam delivering optics was ... [Opt. Express 16, 10279-10284 (2008)]
Sunbathing Frog May Hold Clue To Deadly Diseaseredorbit.com (Jun 24 2008)
Dermatology
"I had been working on a new imaging technology called Optical Coherence Tomography (OCT) for medical imaging,” said Dr Mark Dickinson. ...
Sun-loving frogs aid fungus fightBBC NEWS (Jun 24 2008)
Dermatology
Dr Mark Dickinson said: "I had been working on a new imaging technology called Optical Coherence Tomography (OCT) for medical imaging. ...
Combined Raman-OCT imager targets skin cancer
optics.org (Jun 17 2008)
Dermatology
The first system to combine Raman spectroscopy and optical coherence tomography could improve the diagnosis of skin cancers.
Skin optical clearing enhancement with penetration enhancer azone using spectroscopy and optical coherence tomography
SPIE Digital Library (Jun 9 2008)
Dermatology
Xiangqun Xu and Qiuhong Zhu In order to find a non-invasive way to improve the efficacy of skin optical clearing with topically applied optical clearing agents (OCA), we evaluated the effect of azone ® (epsilon-Laurocapram) as a chemical penetration enhancer on optical clearing of intact skin in vitro. Fresh porcine skin ... [Proc. SPIE 6791, 67910F (2008)] published Mon Jun 9, 2008.
Parallel frequency-domain optical coherence tomography scatter-mode imaging of the hamster cheek pouch using a thermal light source
opticsinfobase.org (May 30 2008)
Dermatology
R. N. Graf, W. J. Brown, A. Wax. We use a parallel frequency-domain optical coherence tomography (FDOCT) system to generate a scatter-mode image of the hamster cheek pouch epithelium. To our knowledge, this is the first optical coherence tomography (OCT) image of a biological sample obtained using a thermal light source in the ... [Opt. Lett. 33, 1285-1287 (2008)]
Impact of shaving and anti-perspirant use on the axillary vault.
NCBI HomePage (May 21 2008)
Dermatology
Related Articles Impact of shaving and anti-perspirant use on the axillary vault. Int J Cosmet Sci. 2007 Feb;29(1):31-8 Authors: Turner GA, Moore AE, Marti VP, Paterson SE, James AG Shaving the axilla is a regular part of the personal care regime for many women in Europe, North and South America. To assess the impact of shaving on underarm skin, a series of investigations were carried out, in which the thickness ...
Maximum-intensity-projection images for dynamic analysis of mental sweating by optical coherence tomography
SPIE Digital Library (May 16 2008)
Dermatology
Hiroyuki Saigusa, Yoshihiro Ueda, Akihiro Yamada et al. We demonstrate a novel 3-D image construction method with maximum intensity projection (MIP) of B-mode images obtained by the swept-source OCT. The time-sequential MIP images with a frame spacing of only 0.7 sec are obtained to make dynamic analysis of mental sweating on human fingertips. ... [Proc. SPIE 7004, 70040V (2008)] published Fri May 16, 2008.
Emerging Alternatives May Lead to End of Biopsies
redorbit.com (May 15 2008)
Dermatology
Lightlab's "optical coherence tomography," pioneered at Massachusetts Institute of Technology, uses an ultrathin fiber-optic cable to deliver infrared light ...
Assessment of Dermal Wound Repair after Collagen Implantation with Optical Coherence Tomography
Mary Ann Liebert, Inc. (May 6 2008)
Dermatology
We present an animal study to examine the utility and potential limitations of optical coherence tomography (OCT) for noninvasive evaluation of biomaterial scaffold–assisted wound healing. The transverse and axial resolutions of the OCT system at the wavelength of 1.3 μm were 12 and 10 μm, respectively. A murine full-thickness transcutaneous wound model was employed, in which a 10 mm full-thickness wound was created on the back of each male Balb/cJ ...
Assessment of dermal wound repair after collagen implantation with optical coherence tomography.
NCBI HomePage (May 6 2008)
Dermatology
Assessment of dermal wound repair after collagen implantation with optical coherence tomography. Tissue Eng Part C Methods. 2008 Mar;14(1):35-45 Authors: Wang Z, Pan H, Yuan Z, Liu J, Chen W, Pan Y We present an animal study to examine the utility and potential limitations of optical coherence tomography (OCT) for noninvasive evaluation of biomaterial scaffold-assisted wound healing. The transverse and axial resolutions of the OCT system at the wavelength of ...
Effect on blood glucose monitoring of skin pressure exerted by an optical coherence tomography probe
SPIE Digital Library (Apr 25 2008)
Dermatology,
Glucose
Veronika V. Sapozhnikova, Roman V. Kuranov, Inga Cicenaite et al. We proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose monitoring, and recently we significantly improved the sensitivity of this technique. The accuracy of OCT glucose monitoring is limited by several factors, including variation of tissue pressure exerted by ... [J. Biomed. Opt. 13, 021112 (2008)] published Fri Apr 25, 2008.
Research Pushes Back Threshold of Early Cancer Detection
UANews.org (Apr 14 2008)
Dermatology
The new technology uses light to detect pre-cancerous cells. Early detection is the single, most important factor in cancer survival. That’s why regular checkups and early testing are so necessary. Unfortunately, current testing methodologies have limitations that prevent very early cancer detection. Cell abnormalities have to reach about 1 mm in size before they can be seen by CT, MRI or ultrasound scans. Sometimes problems at the 1 mm scale ...
Human Skin as Arrays of Helical Antennas in the Millimeter and Submillimeter Wave Range
Scitation (Mar 27 2008)
Dermatology
Author(s): Yuri Feldman, Alexander Puzenko, Paul Ben Ishai, Andreas Caduff, and Aharon J. AgranatRecent studies of the minute morphology of the skin by optical coherence tomography showed that the sweat ducts in human skin are helically shaped tubes, filled with a conductive aqueous solution. A computer simulation study of these structures in millimeter and submillimeter wave bands show that th...[Phys. Rev. Lett. 100, 128102] Published Thu Mar 27, 2008
Machine-learning classification of non-melanoma skin cancers from image features obtained by optical coherence tomography
Blackwell Synergy (Mar 20 2008)
Dermatology
Background/purpose: A number of publications have suggested that optical coherence tomography (OCT) has the potential for non-invasive diagnosis of skin cancer. Currently, individual diagnostic features do not appear sufficiently discriminatory. The combined use of several features may however be useful. Methods: OCT is based on infrared light, photonics and fibre optics. The system used has an axial resolution of 10 μm, lateral 20 μm. We investigated the combined use of ...
Morphology and Epidermal Thickness of Normal Skin Imaged by Optical Coherence Tomography.
NCBI HomePage (Mar 1 2008)
Dermatology
Related Articles Morphology and Epidermal Thickness of Normal Skin Imaged by Optical Coherence Tomography. Dermatology. 2008 Feb 29;217(1):14-20 Authors: Mogensen M, Morsy HA, Thrane L, Jemec GB Background: Optical coherence tomography (OCT) is an optical imaging technology with a potential in the non-invasive diagnosis of skin cancer. To identify skin pathologies using OCT, it is of prime importance to establish baseline morphological features of normal skin. Aims: The aim of ...
In vivo reflectance-mode confocal microscopy in clinical dermatology and cosmetology
Blackwell Synergy (Feb 24 2008)
Dermatology,
Microscopy
In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging tool that allows real-time visualization of cells and structures in living skin with near histological resolution. RCM has been used for the assessment of benign and malignant lesions, showing great potential for applications in basic skin research and clinical dermatology. RCM also reveals dynamic changes in the skin over time and in response to specific stimuli, like ultraviolet exposure, which ...
Sonophoretic Delivery for Contrast and Depth Improvement in Skin Optical Coherence Tomography
IEEE Xplore (Feb 21 2008)
Dermatology
Our previous studies demonstrated the feasibility of using a sonophoretic delivery method to enhance skin light transmittance with topical application of optical clearing agents using spectroscopy. In this study, we examined the effect of ultrasound [surgeon-performed (SP)] on optical coherence tomography (OCT) imaging depth and contrast of in vitro and in vivo skin. Sixty percent glycerol (G) and SP with a frequency of 1 MHz and a power of 0.75 ...
Specular reflection vs. backscattering for transdermal OCT-based glucose monitoring with an implantable sensor system
SPIE Digital Library (Feb 20 2008)
Dermatology,
Glucose
Alexander I. Kholodnykh, Ralph Ballerstadt, Adam Boretsky et al. The reliability of optical techniques for non-invasive monitoring of glucose can be significantly improved by the deployment of a subcutaneous implantable sensor that can closely track the changes in the local concentration of glucose in skin. We have developed a novel implantable sensor that can tr ... [Proc. SPIE Int. Soc. Opt. Eng. 6863, 686306 (2008)] published Wed Feb 20, 2008.
Method and device for calculating a biological component density of a subject
PatFT, AppFT (Feb 19 2008)
Dermatology,
Patents
A method for calculating a biological component density of this invention comprises steps of irradiating a light of NIR spectrum to a skin of a subject, receiving the light of NIR reflected from the skin to obtain NIR spectrum data thereof, and substituting the NIR spectrum data into a predetermined calibrating equation to obtain a biological component density of the subject such as glucose density. This invention is characterized by ...
Gold nanoshells for OCT imaging contrast: From model to in-vivo study
SPIE Digital Library (Feb 13 2008)
Dermatology
E. V. Zagainova, M. V. Shirmanova, A. G. Orlova et al. We have investigated the effect of application of gold nanoshells with a 150 nm silica core size and 25 nm thick gold coating on optical properties of skin. We have analyzed the possibility of using these particles as a contrasting agent for optical coherence tomography (OCT). A set of Monte Carlo c ... [Proc. SPIE Int. Soc. Opt. Eng. ...
Enhancement of light in tissue using hyper-osmotic agents
SPIE Digital Library (Feb 12 2008)
Dermatology
Raiyan T. Zaman, Bo Chen, Ashwin B. Parthasarathy et al. Optical changes in skin blood flow due to the presence of glycerol were measured from a two-dimensional map of blood flow in skin blood vessels with a dynamic imaging technique using laser speckle. In this study a dorsal skin-flap window was implanted on the hamster skin with and without a hyper-osm ... [Proc. SPIE Int. Soc. Opt. Eng. 6854, 68541F ...
Application of polarization OCT in tissue engineering
SPIE Digital Library (Feb 11 2008)
Dermatology
Ying Yang, Mark Ahearne, Pierre O. Bagnaninchi et al. For tissue engineering of load-bearing tissues, such as bone, tendon, cartilage, and cornea, it is critical to generate a highly organized extracellular matrix. The major component of the matrix in these tissues is collagen, which usually forms a highly hierarchical structure with increasing scale f ... [Proc. SPIE Int. Soc. Opt. Eng. 6858, 68580K (2008)] published Mon Feb 11, 2008.
The evaluation of the photoaging of the human skin by three-dimensional polarization sensitive spectral domain optical coherence tomography
SPIE Digital Library (Feb 8 2008)
Dermatology
Arata Miyazawa, Shingo Sakai, Masayuki Matsumoto et al. Noninvasive evaluation of dermal degeneration is important for a diagnosis of photoaging. Polarization sensitive optical coherence tomography (PS-OCT) can measure the distribution of phase retardation caused by birefringence property of collagen. The PS-OCT has been reported as the technology of in ... [Proc. SPIE Int. Soc. Opt. Eng. 6842, 684207 (2008)] published Fri Feb 8, 2008.