About Guillermo J. Tearney

Guillermo J. Tearney, M.D. Ph.D. is an Associate Professor at the Wellman Center for Photomedicine at Massachusetts General Hospital. Current research interests are primarily focused on the development and validation of non-invasive, high-resolution optical methods for disease diagnosis. As a pathologist, I have a particular emphasis on conducting microscopy in living patients. Projects span early invention to large multidisciplinary clinical trials.

  1. Mentioned In 27 Articles

  2. Apparatus And Method For Simultaneous Inspection At Different Depths Based On The Principle Of Frequency Domain Optical Coherence Tomography (Wo 2008/089406)

    wipo.int (Jul 24 2008) Patents Explore Article

    Exemplary embodiments of an apparatus are provided. For example, the exemplary apparatus can include at least one first arrangement providing at least one first electro- magnetic radiation to a sample, at least one second electro-magnetic radiation to a first reference and at least one third electro-magnetic radiation to a second reference. A frequency of radiation provided by the first arrangement generally varies over time. The exemplary apparatus may also include ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Harvard Medical School

  3. In vivo association between positive coronary artery remodelling ...

    Oxford Journals (Jul 14 2008) Cardiology Explore Article

    1 Cardiology Division, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRB 800, Boston, MA 02114, USA 2 Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA 3 Division of Cardiology, Nippon Medical School, Tokyo, Japan * Corresponding author. Tel: +1 617 726 9226, Fax: +1 617 726 7419, Email: See page 1704 for the editorial comment on this article (doi:10.1093/eurheartj/ehn201) Aims: Positive ...

    Comment on Article Mentions:   Wellman Center for Photomedicine   Harvard Medical School   Massachusetts General Hospital

  4. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography

    Oxford Journals (Jun 26 2008) Cardiology Explore Article

    ...ssed by intravascular optical coherence tomography Owen Christopher Raffel^1, Faisal M. Merchant^1, Guillermo J. Tearney^2, Stanley Chia^1, Denise DeJoseph Gauthier^1, Eugene Pomerantsev^1, Kyoichi Mizuno^3, Brett E. Bou...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

  5. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography.

    NCBI HomePage (Jun 26 2008) Cardiology Explore Article

    In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography. Eur Heart J. 2008 Jun 24; Authors: Raffel OC, Merchant FM, Tearney GJ, Chia S, Dejoseph Gauthier D, Pomerantsev E, Mizuno K, Bouma BE, Jang IK Aims Positive coronary arterial remodelling has been shown to be associated with unstable coronary syndromes and ex vivo histological characteristics of plaque vulnerability such as a ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

  6. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing.

    NCBI HomePage (Jun 11 2008) Explore Article

    Related Articles High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing. Opt Express. 2008 Jan 21;16(2):1096-103 Authors: Oh WY, Yun SH, Vakoc BJ, Shishkov M, Desjardins AE, Park BH, de Boer JF, Tearney GJ, Bouma BE Polarization sensitive optical coherence tomography (PS-OCT) provides a cross-sectional image of birefringence in biological samples that is complementary in many applications to the standard reflectance-based image. Recent ex vivo studies have demonstrated that ...

    Comment on Article Mentions:   Harvard Medical School   Wellman Center for Photomedicine   Massachusetts General Hospital

  7. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation

    opticsinfobase.org (Jun 10 2008) Explore Article

    W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, B. E. Bouma. We demonstrate a novel high-speed polarization-sensitive optical frequency domain ima...

    Comment on Article Mentions:   Seok-Hyun Yun   Guillermo J. Tearney   Brett E. Bouma

  8. Fiber-optic rotational device, optical system and method for imaging a sample

    PatFT, AppFT (Jun 3 2008) Cardiology , Endoscopy , Patents Explore Article

    A device, system and method for transmitting electro-magnetic radiation between at least two separate fibers (as well as for imaging a sample) are provided. For example, a first optical fiber and a second optical fiber may be provided, such that the first and/or second fibers is/are rotatable. At least one first optical arrangement may also be included which communicates with at least one end of the first optical fiber and/or ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Harvard Medical School

  9. Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.

    NCBI HomePage (May 16 2008) Cardiology Explore Article

    Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study. Coron Artery Dis. 2008 Jun;19(4):237-42 Authors: Chia S, Raffel OC, Takano M, Tearney GJ, Bouma BE, Jang IK OBJECTIVE: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating ...

    Comment on Article Mentions:   Harvard Medical School   Massachusetts General Hospital   Guillermo J. Tearney

  10. Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.

    Coronary Artery Disease (May 16 2008) Cardiology Explore Article

    Coronary Artery Disease. 19(4):237-242, June 2008. Chia, Stanley a; Raffel, Owen Christopher a; Takano, Masamichi c; Tearney, Guillermo J. b; Bouma, Brett E. b; Jang, Ik-Kyung a Abstract: Objective: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating coronary plaque

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Harvard Medical School

  11. Comparison of coronary plaque characteristics between diabetic and non-diabetic subjects: An in vivo optical coherence tomography study.

    NCBI HomePage (May 6 2008) Cardiology Explore Article

    Comparison of coronary plaque characteristics between diabetic and non-diabetic subjects: An in vivo optical coherence tomography study. Diabetes Res Clin Pract. 2008 May 1; Authors: Chia S, Raffel OC, Takano M, Tearney GJ, Bouma BE, Jang IK AIMS: Postmortem series have reported that subjects with diabetes mellitus have coronary plaques with larger necrotic cores and increased macrophage infiltration. Optical coherence tomography (OCT) is a high-resolution imaging modality that allows in ...

    Comment on Article Mentions:   Harvard Medical School   Massachusetts General Hospital   Guillermo J. Tearney

  12. Evaluation of intracoronary stenting by intravascular optical coherence tomography

    Heart (Apr 7 2008) Cardiology Explore Article

    Wellman Laboratories of Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Background: Conventional contrast cineangiography and intravascular ultrasound (IVUS) provide a limited definition of vessel microstructure and are unable to evaluate dissection, tissue prolapse, and stent apposition on a size scale less than 100 µm. Objective: To evaluate the use of intravascular optical coherence tomography (OCT) to assess the coronary arteries in patients undergoing coronary stenting. Methods: ...

    Comment on Article Mentions:   Harvard Medical School   Massachusetts General Hospital   Guillermo J. Tearney

  13. Simultaneous measurement of refractive index and thickness by combining low-coherence interferometry and confocal optics

    opticsinfobase.org (Apr 4 2008) Microscopy Explore Article

    Seokhan Kim, Jihoon Na, Myoung Jin Kim, Byeong Ha Lee. We propose and demonstrate novel methods that enable simultaneous measurements of the phase index, the group index, and the geometrical thickness of an optically transparent object by combining optical low-coherence interferometer and confocal optics. The low-coherence interferometer gives ... [Opt. Express 16, 5516-5526 (2008)]

    Comment on Article Mentions:   David D. Sampson   Guillermo J. Tearney   Timothy Hillman

  14. Spectroscopic OCT by Grating-Based Temporal Correlation Coupled to Optical Spectral Analysis.

    Hindawi Publishing Corporation (Apr 4 2008) Explore Article

    ..., 1583, Ph.D. thesis, Ecole Polytechnique e Federale de Lausanne, Lausanne, Switzerland, 1996. [22] G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, “High-speed phase- and group-delay scanning with a grating-base...

    Comment on Article Mentions:   James G. Fujimoto   Optovue   Stephen A. Boppart

  15. Characterization of Fourier domain modelocked wavelength swept laser for optical coherence tomography imaging

    opticsinfobase.org (Mar 6 2008) Explore Article

    Min Yong Jeon, Jun Zhang, Zhongping Chen. We present characteristics of a wavelength swept laser with a scanning fiber Fabry-Perot filter at 1300 nm. We investigate the dependence of the scanning frequencies in the swept laser. In conventional wavelength swept lasers, the relative intensity of the laser output decreases significantly as ... [Opt. Express 16, 3727-3737 (2008)]

    Comment on Article Mentions:   Jun Zhang   Joseph A. Izatt   James G. Fujimoto

  16. Real-time interferometric synthetic aperture microscopy

    opticsinfobase.org (Feb 12 2008) Microscopy Explore Article

    Tyler S. Ralston, Daniel L. Marks, P. S. Carney, Stephen A. Boppart. An interferometric synthetic aperture microscopy (ISAM) system design with real-time 2D cross-sectional processing is described in detail. The system can acquire, process, and display the ISAM reconstructed images at frame rates of 2.25 frames per second for 512 X 1024 pixel images. This system ... [Opt. Express 16, 2555-2569 (2008)]

    Comment on Article Mentions:   Joseph A. Izatt   Brett E. Bouma   Seok-Hyun Yun

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