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Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques
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About Ik-Kyung Jang
Ik-Kyung Jang, MD, PHD, Cardiology Division, Massachusetts General Hospital and Harvard Medical School.
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Mentioned In 8 Articles
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Distance From the Coronary Ostium as a Predictor of Vulnerable Plaque Morphology; An In-vivo Optical Coherence Tomography Study
Circulation (Nov 10 2008) Cardiology Explore Article
...hickness Owen C Raffel; Guillermo J Tearney; Stanley Chia; Denise DeJoseph Gauthier; Brett E Bouma; Ik-Kyung Jang Massachusetts General Hosp & Harvard Med Sch, Boston, MA Background: Plaque morphology predicts its...
(Read Full Article)
Comment on Article Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital
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Comparison of coronary plaque characteristics between diabetic and non-diabetic subjects: An in vivo optical coherence tomography study
ScienceDirect (Aug 15 2008) Cardiology Explore Article
Aims Postmortem series have reported that subjects with diabetes mellitus have coronary plaques with larger necrotic cores and increased macrophage infiltration. Optical coherence tomography (OCT) is a high-resolution imaging modality that allows in vivo characterization of atherosclerotic plaques. Using OCT imaging, we compared in vivo plaque characteristics between diabetic and non-diabetic subjects. Methods Sixty-three patients undergoing cardiac catheterization were enrolled. OCT imaging was performed in culprit coronary arteries. Assessment of ... (Read Full Article)
Comment on Article Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital
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Cardiac Optical Coherence Tomography
Heart (Aug 13 2008) Cardiology Explore Article
Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially treat these ... (Read Full Article)
Comment on Article Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
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In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography
Oxford Journals (Jul 14 2008) Cardiology Explore Article
Aims: Positive coronary arterial remodelling has been shown to be associated with unstable coronary syndromes and ex vivo histological characteristics of plaque vulnerability such as a large lipid core and high macrophage content. The aim of this study is to evaluate the in vivo association between coronary artery remodelling and underlying plaque characteristics identified by optical coherence tomography (OCT). OCT is a unique imaging modality capable of characterizing these important ... (Read Full Article)
Comment on Article Mentions: Massachusetts General Hospital Guillermo J. Tearney Brett E. Bouma
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Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.
Coronary Artery Disease (May 16 2008) Cardiology Explore Article
Coronary Artery Disease. 19(4):237-242, June 2008. Chia, Stanley a; Raffel, Owen Christopher a; Takano, Masamichi c; Tearney, Guillermo J. b; Bouma, Brett E. b; Jang, Ik-Kyung a Abstract: Objective: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating coronary plaque (Read Full Article)
Comment on Article Mentions: Guillermo J. Tearney Brett E. Bouma Ik-Kyung Jang
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Evaluation of intracoronary stenting by intravascular optical coherence tomography
Heart (Apr 7 2008) Cardiology Explore Article
Wellman Laboratories of Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Background: Conventional contrast cineangiography and intravascular ultrasound (IVUS) provide a limited definition of vessel microstructure and are unable to evaluate dissection, tissue prolapse, and stent apposition on a size scale less than 100 µm. Objective: To evaluate the use of intravascular optical coherence tomography (OCT) to assess the coronary arteries in patients undergoing coronary stenting. Methods: ... (Read Full Article)
Comment on Article Mentions: Massachusetts General Hospital Guillermo J. Tearney Brett E. Bouma
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In Vivo Comparison of Optical Coherence Tomography and Angioscopy for the Evaluation of Coronary Plaque Characteristics
ScienceDirect (Feb 6 2008) Cardiology Explore Article
Atherosclerotic yellow plaques identified by coronary angioscopy are considered as vulnerable plaques. However, characteristics of yellow plaques are not well understood. Optical coherence tomography (OCT) provides accurate tissue characterization in vivo and has the capability to measure fibrous cap thickness covering a lipid plaque. Characteristics of yellow plaques identified by angioscopy were evaluated by OCT. We examined 205 plaques of 41 coronary arteries in 26 patients. In OCT analysis, plaques ... (Read Full Article)
Comment on Article Mentions: Masamichi Takano Ik-Kyung Jang Masanori Yamamoto
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Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques
google (Nov 4 2007) Cardiology Explore Article
...artery disease every year, a quarter of them before or soon after arriving at the hospital,” says Ik-Kyung Jang, MD, PhD, director of cardiovascular clinical research in the MGH Cardiology Division and lead auth... (Read Full Article)
Comment on Article Mentions: Masamichi Takano Massachusetts General Hospital Ik-Kyung Jang






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