About Massachusetts General Hospital

Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center). The Wellman Center for Photomedicine at Massachusetts General Hospital is the world’s largest academic research facility dedicated to investigating the effects of light on human biology and to the development of light-mediated, minimally invasive diagnostic and therapeutic technologies. A pioneer in light-based biomedical research, the Center has been the source of many of the most successful transfers of this research to clinical applications.  

  1. Mentioned In 37 Articles

  2. Doppler imaging using spectrally-encoded endoscopy

    opticsinfobase.org (Sep 5 2008) Explore Article

    Dvir Yelin, B. E. Bouma, J. J. Rosowsky, G. J. TearneyThe capability to image tissue motion such as blood flow through an endoscope could have many applications in medicine. Spectrally encoded endoscopy (SEE) is a recently introduced technique that utilizes a single optical fiber and miniature diffractive optics to obtain endoscopic images through ... [Opt. Express 16, 14836-14844 (2008)]

    Comment on Article Mentions:   Brett E. Bouma   Guillermo J. Tearney   Superlum

  3. Apparatus for controlling at least one of at least two sections of at least one fiber

    PatFT, AppFT (Aug 26 2008) Endoscopy , Microscopy , Patents Explore Article

    FIELD OF THE INVENTION The present invention relates to apparatus for controlling a fiber, and more particularly to apparatus for controlling at least one of at least two sections of at least one fiber.BACKGROUND INFORMATIONA use of lasers for ablating or thermally destroying diseased tissue is known and at time preferred, primarily due to the potential for precise local effect with minimal collateral damage. In practice, however, laser therapy has ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

  4. Cardiac Optical Coherence Tomography

    Heart (Aug 13 2008) Cardiology Explore Article

    Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially treat these ...

    Comment on Article Mentions:   Massachusetts General Hospital   Ik-Kyung Jang   Harvard University

  5. In vivo fluorescence microscopy imaging & optical coherence tomography (Harvard University)

    Nature Publishing Group (Aug 12 2008) Jobs & Studentships Explore Article

    Research positions are available for the following projects: 1. In vivo cellular imaging in small animals (mice models): develop and operate confocal and multiphoton microscopes, engaged in multiple collaborative projects with biologists and biomedical scientists, develop techniques for mouse fluorescence endo-microscopy, immune/stem cell trafficking, tissue microenvironmental sensing. Successful candidates should have experience in microscopy, knowledge in basic biology, and excellent ver…

    Comment on Article Mentions:   Massachusetts General Hospital   Harvard University

  6. Spectral Domain Optical Coherence Tomography for Quantitative Evaluation of Drusen and Associated Structural Changes in Non-Neovascular Age Related Macular Degeneration

    BJO Online (Aug 11 2008) Ophthalmology Explore Article

    ... University, Korea, Republic of ^2 Physical Sciences Inc., Andover, Massachusetts, United States ^3 Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States ^4 Boston University, Department of Physics, Boston, Massachu...

    Comment on Article Mentions:   Zeiss Stratus OCT   Tufts University School of Medicine   Massachusetts General Hospital

  7. Apparatus And Method For Simultaneous Inspection At Different Depths Based On The Principle Of Frequency Domain Optical Coherence Tomography (Wo 2008/089406)

    wipo.int (Jul 24 2008) Patents Explore Article

    Exemplary embodiments of an apparatus are provided. For example, the exemplary apparatus can include at least one first arrangement providing at least one first electro- magnetic radiation to a sample, at least one second electro-magnetic radiation to a first reference and at least one third electro-magnetic radiation to a second reference. A frequency of radiation provided by the first arrangement generally varies over time. The exemplary apparatus may also include ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Harvard University

  8. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography

    Oxford Journals (Jul 14 2008) Cardiology Explore Article

    ...ined as lipid-rich plaque (two or more quadrants) with fibrous cap thickness 1 Cardiology Division, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRB 800, Boston, MA 02114, USA 2 Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA 3 Division of Cardiology, Nippon Medical School, Tokyo,...

    Comment on Article Mentions:   Massachusetts General Hospital   Guillermo J. Tearney   Brett E. Bouma

  9. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation

    opticsinfobase.org (Jun 10 2008) Explore Article

    W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, B. E. Bouma. We demonstrate a novel high-speed polarization-sensitive optical frequency domain imaging system employing high-speed polarization modulation. Rapid and continuous polarization modulation of light prior to illumination of the sample is accomplished by shifting the frequency of one polarization ... [Opt. Lett. 33, 1330-1332 (2008)]

    Comment on Article Mentions:   Seok-Hyun Yun   Guillermo J. Tearney   Brett E. Bouma

  10. Fiber-optic rotational device, optical system and method for imaging a sample

    PatFT, AppFT (Jun 3 2008) Cardiology , Endoscopy , Patents Explore Article

    A device, system and method for transmitting electro-magnetic radiation between at least two separate fibers (as well as for imaging a sample) are provided. For example, a first optical fiber and a second optical fiber may be provided, such that the first and/or second fibers is/are rotatable. At least one first optical arrangement may also be included which communicates with at least one end of the first optical fiber and/or ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

  11. Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.

    Coronary Artery Disease (May 16 2008) Cardiology Explore Article

    Coronary Artery Disease. 19(4):237-242, June 2008. Chia, Stanley a; Raffel, Owen Christopher a; Takano, Masamichi c; Tearney, Guillermo J. b; Bouma, Brett E. b; Jang, Ik-Kyung a Abstract: Objective: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating coronary plaque

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Ik-Kyung Jang

  12. Comparison of coronary plaque characteristics between diabetic and non-diabetic subjects: An in vivo optical coherence tomography study.

    NCBI HomePage (May 6 2008) Cardiology Explore Article

    ... tomography study. Chia S, Raffel OC, Takano M, Tearney GJ, Bouma BE, Jang IK. Cardiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street GRB 800, Boston, MA, United States. AIMS: Postmortem serie...

    Comment on Article Mentions:   Massachusetts General Hospital   Guillermo J. Tearney   Brett E. Bouma

  13. System and method for optical coherence imaging

    PatFT, AppFT (Apr 29 2008) Patents Explore Article

    Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

  14. System and method for optical coherence imaging

    PatFT, AppFT (Apr 29 2008) Patents Explore Article

    A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one second ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Johannes F. de Boer

  15. In-vivo three-dimensional imaging of neovascular age related macular degeneration using optical frequency domain imaging at 1050 nm.

    NCBI HomePage (Apr 9 2008) Ophthalmology Explore Article

    ...ng OFDI, a swept-source based high-speed optical coherence tomography (OCT) system developed at the Wellman Center for Photomedicine. We used a center wavelength of 1050 nm which has previously been demonstrated to provide better im...

    Comment on Article Mentions:   Johannes F. de Boer   Massachusetts Eye and Ear Infirmary   Teresa C. Chen

  16. Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands

    PatFT, AppFT (Apr 8 2008) Patents Explore Article

    Apparatus, method, logic arrangement and storage medium are provided for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry ("LCI") signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source can be split into N spectral bands. The N spectral bands can be individually detected and processed to provide an increase in ...

    Comment on Article Mentions:   Guillermo J. Tearney   Brett E. Bouma   Johannes F. de Boer

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