About Massachusetts Institute of Technology

Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.

  1. Mentioned In 95 Articles

  2. Multiple beams boost resolution of OCT

    BioOptics World (Nov 18 2008) Explore Article

    Optical coherence tomography (OCT), a powerful cross-sectional modality allowing noninvasive imaging of samples in real time and at high resolution, has become the new gold standard in ophthalmic care. But while it is extremely promising for other clinical applications, its use in those areas is not widespread. That is due at least in part to technical constraints, which equipment makers are addressing. One approach, multibeam OCT, promises to advance the ... (Read Full Article)

    Comment on Article Mentions:   Michelson Diagnostics   Victor Yang   Yamagata University

  3. Optical Coherence Tomography Poised to Improve Diagnostics

    nibib.nih.gov (Nov 10 2008) Endoscopy Explore Article

    ... ago, using technology that would revolutionize the telecommunications industry, researchers at the Massachusetts Institute of Technology developed an elegant optical imaging technique—optical coherence tomography (OCT). The technique,... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   Stephen A. Boppart   University of Illinois at Urbana-Champaign

  4. Ultrahigh-Speed Optical Coherence Tomography for Three-Dimensional and En Face Imaging of the Retina and Optic Nerve Head

    iovs.org (Oct 28 2008) Ophthalmology Explore Article

    Ultrahigh-speed swept-source optical coherence tomography (OCT) imaging of the retina and optic nerve is demonstrated at 249,000 axial scans per second and 1060 nm, while methods for en face visualization of the retina, choroid, and lamina cribrosa are investigated. (Read Full Article)

    Comment on Article Mentions:   Desmond C. Adler   University of Pittsburgh   Massachusetts Institute of Technology

  5. Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation

    opticsinfobase.org (Oct 28 2008) Explore Article

    Benjamin R. Biedermann, Wolfgang Wieser, Christoph M. Eigenwillig, Gesa Palte, Desmond C. Adler, Vivek J. Srinivasan, James G. Fujimoto, Robert Huber We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a k-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, ... [Opt. Lett. 33, 2556-2558 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Desmond C. Adler   Massachusetts Institute of Technology

  6. Three Dimensional Optical Coherence Tomography (3D-OCT) Image Enhancement with Segmentation Free Contour Modeling C-Mode

    iovs.org (Oct 28 2008) Ophthalmology Explore Article

    ... Medical Center, Boston, Massachusetts, United States; New England Medical Center, United States ^5 Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Cambr... (Read Full Article)

    Comment on Article Mentions:   University of Pittsburgh   Massachusetts Institute of Technology   James G. Fujimoto

  7. Doheny Eye Institute Researcher, David Huang, MD, PhD, Receives $7 Million in a Five Year Grant Renewal for Studying Ocular Imaging for the Diagnosis and Monitoring of Glaucoma

    Optical Coherence Tomography News (Oct 9 2008) Ophthalmology , Funding Explore Article

    ...principal investigator and study chairman at DEI, USC James G. Fujimoto, PhD, engineering center at Massachusetts Institute of Technology David Greenfield, MD, clinical center at University of Miami (UM), Bascom Palmer Eye Institute (BPE... (Read Full Article)

    Comment on Article Mentions:   University of Pittsburgh   Massachusetts Institute of Technology   James G. Fujimoto

  8. Synthetic aperture tomographic phase microscopy for 3D imaging of live cells in translational motion

    opticsinfobase.org (Sep 26 2008) Microscopy Explore Article

    Niyom Lue, Wonshik Choi, Gabriel Popescu, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld We present a technique for 3D imaging of live cells in translational motion without need of axial scanning of objective lens. A set of transmitted electric field images of cells at successive points of transverse translation is taken with a focused beam illumination. Based on Hyugens’ ... [Opt. Express 16, 16240-16246 (2008)] (Read Full Article)

    Comment on Article Mentions:   Wonshik Choi   Massachusetts Institute of Technology   Michael S. Feld

  9. A Brief History of Optical Coherence Tomography: A Personal Perspective

    osli.com (Sep 11 2008) Ophthalmology Explore Article

    The historical highlights of the development of optical coherence tomography (OCT) are reviewed as an introduction to a journal issue devoted to spectral domain OCT. [Ophthalmic Surg Lasers Imaging 2008;39:S6-S7.] (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   James G. Fujimoto   David Huang

  10. Ultrahigh speed Spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second

    opticsinfobase.org (Sep 11 2008) Ophthalmology Explore Article

    James G. Fujimoto, Benjamin Potsaid, Iwona Gorczynska, Vivek Srinivasan, Yueli Chen, James Jiang, Alex Cable We demonstrate ultrahigh speed spectral / Fourier domain optical coherence tomography (OCT) using an ultrahigh speed CMOS line scan camera at rates of 70,000 - 312,500 axial scans per second. Several design configurations are characterized to illustrate trade-offs between acquisition speed, ... [Opt. Express 16, 15149-15169 (2008)] (Read Full Article)

    Comment on Article Mentions:   James G. Fujimoto   Massachusetts Institute of Technology   Thorlabs

  11. Analysis of the Outer Retina Reconstructed by High-resolution, Three-dimensional Spectral Domain Optical Coherence Tomography

    osli.com (Sep 10 2008) Ophthalmology Explore Article

    ...e Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts (JGF); New England Eye Center, Tufts-New England Medical Center, Tufts Un... (Read Full Article)

    Comment on Article Mentions:   University of Pittsburgh   Massachusetts Institute of Technology   James G. Fujimoto

  12. Fujimoto plenary gets Photon '08 going

    optics.org (Aug 27 2008) Explore Article

    Photon 08 kicked off with a plenary talk from James Fujimoto of MIT, US, who described the current state of the art in optical coherence tomography (OCT). "OCT is on its way to becoming an accepted clinical methodology," he said. Fourier domain analysis has already opened up new applications for the technology, and now high-speed high-resolution OCT is becoming a reality. "Fourier domain modelocked swept-source OCT can allow a 20 ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto

  13. Mode locking methods and apparatus

    PatFT » Page 1 of 1 (Aug 19 2008) Patents Explore Article

    FIELD OF THE INVENTIONT he invention relates generally to the field of wave generation. In particular, the invention relates to Fourier Domain Mode Locking (FDML) and applications thereof. BACKGROUND OF THE INVENTIONIn many industries and technical areas of research, various systems and devices are used to obtain precise measurements or imaging. In conjunction with the need for precision, there is also a demand for high speed data collection. To satisfythese ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Robert Huber

  14. Reconfigurable polarization independent interferometers and methods of stabilization

    PatFT » Page 1 of 1 (Aug 19 2008) Patents Explore Article

    BACKGROUND OF THE INVENTIONOptical interferometers are used in optical receivers to receive optical communications signals, such as Differential Phase Shift Keyed (DPSK) modulation signals, which carries differentially encoded data on the phase of an optical signal intime. DPSK provides approximately 3 dB sensitivity improvement over commonly used intensity modulation (IM) formats, such as On Off Keying (OOK). It also can operate with a 100% duty-cycle, in contrast to the IM ... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology

  15. Phase-Conjugate Optical Coherence Tomography Methods And Apparatus (Wo 2008/091286)

    wipo.int (Jul 31 2008) Patents Explore Article

    ...t of photon-... (WO/2008/091286) PHASE-CONJUGATE OPTICAL COHERENCE TOMOGRAPHY METHODS AND APPARATUS MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue, Cambridge, MA 02139 (US) (All Except US). ERKMEN, Baris, I. [US/U... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology

  16. Projection OCT fundus imaging for visualizing outer retinal pathology in non-exudative age related macular degeneration

    BJO Online (Jul 27 2008) Ophthalmology Explore Article

    ...as Reichel ^2, Maciej Wojtkowski ^3, Joel S Schuman ^4, Jay S Duker ^2 and James G Fujimoto ^1^* ^1 Massachusetts Institute of Technology, United States ^2 Tufts-New England Medical Center, New England Eye Center, United States ^3 Instit... (Read Full Article)

    Comment on Article Mentions:   Massachusetts Institute of Technology   James G. Fujimoto   Maciej Wojtkowski

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