About Thoraxcenter at Erasmus University Medical Center

The Thoraxcentrum of the Erasmus University Medical Center was founded in 1971 and is an integrated organization of the departments of Cardiology and Cardiothoracic Surgery. The Thoraxcentrum is divided into six medical units and three scientific units: Cardio-Thoracic Surgery, Cardiology, and Biomedical Engineering. The focus of Thoraxcenter Biomedical Engineering is the imaging and diagnosis of cardiovascular disorders. This department is led by Prof. Dr. Ir. A.F.W. van der Steen. The Biomedical Engineering department brings together two technical specialities of the Thoraxcenter, namely: The Experimental Echocardiography group, which investigates the physical and technical aspects of ultrasound for cardiac diagnosis.  Erasmus University Rotterdam is an international knowledge workshop for critical thinking and academic training, driven by a strong focus on current social issues. The university concentrates its expertise on issues of management, organisation and policy in the public and private sectors on the one hand, as well as on the field of sickness and health care. Erasmus University Rotterdam has bundled its education and research in three domains in which the university has a national and international reputation: Economics and Management; Medicine and Health Sciences; Law, Culture and Society.

  1. Mentioned In 23 Articles

  2. Optical Coherence Tomography Findings At Two Years Follow Up In Fully Biodegradable Everolimus Eluting Stents

    Circulation (Nov 10 2008) Cardiology Explore Article

    Fully biodegradable stents may avoid the potential long-term complications of metallic drug-eluting stents such as late and very late stent thrombosis. We sought to evaluate the structural changes in a bioabsorbable DES and its interaction with the coronary vessel wall over time using optical coherence tomography (OCT). We investigated 14 consecutive patients undergoing implantation of a bioabsorbable everolimus-eluting coronary stent (BVS: Abbott Laboratories, IL, USA), composed of a poly-L-lactic acid ... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Evelyn Regar   Thoraxcenter at Erasmus University Medical Center

  3. iosensors DES Demonstrates Superior Strut Coverage to Industry Leading DES

    pharmiweb.com (Oct 16 2008) Cardiology Explore Article

    ...-month resultsâ€?, commented Professor Patrick Serruys, head of the interventional department at Erasmus University’s Thoraxcenter in Rotterdam, The Netherlands. “The Biosensors drug eluting stent, combining the novel biolim... (Read Full Article)

    Comment on Article Mentions:   Carlo Di Mario   Royal Brompton Hospital   Patrick W. Serruys

  4. Optical coherence tomography: clinical applications and the evaluation of DES.

    NCBI HomePage (Sep 25 2008) Cardiology Explore Article

    ...erence tomography: clinical applications and the evaluation of DES. Gonzalo N, Serruys PW, Regar E. Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands e.regar@erasmusmc.nl. Optical coherencet tomogr... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Thoraxcenter at Erasmus University Medical Center   Evelyn Regar

  5. Multi-modality intra-coronary plaque characterization: A pilot study☆

    International Journal of Cardiology (Sep 9 2008) Cardiology Explore Article

    ...t imaging resolutions and the lack of common nomenclature and classification. Corresponding author. Thoraxcenter, Bd 585,'s-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. Tel.: +31 10 70 35729; fax: +31 1... (Read Full Article)

    Comment on Article Mentions:   Peter Barlis   Royal Brompton Hospital   Patrick W. Serruys

  6. The influence of strut thickness and cell design on immediate apposition of drug-eluting stents assessed by optical coherence tomography

    International Journal of Cardiology (Sep 9 2008) Cardiology Explore Article

    Background Stent strut malapposition correlates with poor intimal coverage and this may increase the risk of late stent thrombosis. At present, there is limited data on whether stent strut thickness and stent design impact on acute apposition. We aimed to investigate the influence of stent strut thickness and design on acute stent strut apposition (SSA) immediately following drug-eluting stent (DES) implantation using optical coherence tomography (OCT), a technique with higher ... (Read Full Article)

    Comment on Article Mentions:   Jun Tanigawa   Carlo Di Mario   Peter Barlis

  7. The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture

    International Journal of Cardiology (Sep 1 2008) Cardiology Explore Article

    Drug-eluting stents (DES) have made a tremendous impact on the practice of percutaneous coronary intervention. Recently however, long-term DES failures have become a focal point, particularly with restenosis and thrombosis. An uncommon, yet important cause of DES failure is stent fracture. Of the two established first generation DES, the sirolimus-eluting stent (SES) has been particularly linked to cases of stent fracture, likely as a result of its closed cell design ... (Read Full Article)

    Comment on Article Mentions:   Carlo Di Mario   Peter Barlis   Thoraxcenter at Erasmus University Medical Center

  8. Optical Coherence Tomography Findings in Very Late (4 Years) Paclitaxel-Eluting Stent Thrombosis

    interventions.onlinejacc.org (Aug 18 2008) Cardiology Explore Article

    No Abstract Provided (Read Full Article)

    Comment on Article Mentions:   Peter Barlis   Patrick W. Serruys   Evelyn Regar

  9. Assessment of Culprit and Remote Coronary Narrowings Using Optical Coherence Tomography With Long-Term Outcomes

    American Journal of Cardiology (Aug 18 2008) Cardiology Explore Article

    Much currently known information about vulnerable plaque stems from postmortem studies that identified several characteristics making them prone to rupture, including the presence of a thin fibrous cap and a large lipid core. This study used optical coherence tomography (OCT) to assess culprit and remote coronary narrowings and investigate whether intracoronary OCT in living patients was able to visualize morphologic features associated with vulnerable plaque in postmortem studies. Twenty-three patients ... (Read Full Article)

    Comment on Article Mentions:   Peter Barlis   Patrick W. Serruys   Evelyn Regar

  10. Azimuthal Registration of Image Sequences Affected by Nonuniform Rotation Distortion

    IEEE Xplore (Aug 13 2008) Cardiology Explore Article

    Imaging modalities that use a mechanically rotated endoscopic probe to scan a tubular volume, such as an artery, often suffer from image degradation due to nonuniform rotation distortion (NURD). In this paper, we present a new method to align individual lines in a sequence of images. It is based on dynamic time warping, finding a continuous path through a cost matrix that measures the similarity between regions of two frames ... (Read Full Article)

    Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   Gijs van Soest   Anton F. W. van der Steen

  11. Assessment of culprit and remote coronary narrowings using optical coherence tomography with long-term outcomes.

    NCBI HomePage (Aug 6 2008) Cardiology Explore Article

    ...th long-term outcomes. Barlis P, Serruys PW, Gonzalo N, van der Giessen WJ, de Jaegere PJ, Regar E. Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands. Much currently known information about vulnera... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Thoraxcenter at Erasmus University Medical Center   Peter Barlis

  12. Diagnosis of Vertical Root Fractures with Optical Coherence Tomography

    jendodon.com (May 24 2008) Dentistry Explore Article

    The purpose of this experiment was to evaluate the ability of optical coherence tomography (OCT) to image vertical root fractures (VRFs). Twenty-five mandibular premolars were prepared to size 50. Five teeth served as controls. Group 1 (n = 10) was treated with ethylenediaminetetraacetic acid and ultrasonic irrigation, whereas group 2 (n = 10) received no further treatments. Teeth from groups 1 and 2 were fractured, and the presence of a ... (Read Full Article)

    Comment on Article Mentions:   Gijs van Soest   Thoraxcenter at Erasmus University Medical Center

  13. Diagnosis of vertical root fractures with optical coherence tomography.

    NCBI HomePage (May 24 2008) Dentistry Explore Article

    Related Articles Diagnosis of vertical root fractures with optical coherence tomography. J Endod. 2008 Jun;34(6):739-42 Authors: Shemesh H, van Soest G, Wu MK, Wesselink PR The purpose of this experiment was to evaluate the ability of optical coherence tomography (OCT) to image vertical root fractures (VRFs). Twenty-five mandibular premolars were prepared to size 50. Five teeth served as controls. Group 1 (n = 10) was treated with ethylenediaminetetraacetic acid and ... (Read Full Article)

    Comment on Article Mentions:   Gijs van Soest   Thoraxcenter at Erasmus University Medical Center

  14. Volcano Corp announces 1st human use of Volcano optical catheter

    ANTARA News (May 12 2008) Cardiology Explore Article

    ...e using the Volcano OCT Imaging catheter. The procedure was performed by Dr. Patrick Serruys at the Thoraxcenter, in Rotterdam, Netherlands. Volcano OCT will complement its existing line of IVUS imaging catheters... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Michel Lussier   Scott Huennekens

  15. Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma

    Oxford Journals (Apr 30 2008) Cardiology Explore Article

    ...University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan 2 Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands * Corresponding author. Tel: +81 78 382 5846, Fax: +81 78 3... (Read Full Article)

    Comment on Article Mentions:   Patrick W. Serruys   Thoraxcenter at Erasmus University Medical Center   Hector M. Garcia-Garcia

  16. A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial.

    HubMed (Mar 29 2008) Cardiology Explore Article

    BACKGROUND: A fully bioabsorbable drug-eluting coronary stent that scaffolds the vessel wall when needed and then disappears once the acute recoil and constrictive remodelling processes have subsided has theoretical advantages. The bioasorbable everolimus-eluting stent (BVS) has a backbone of poly-L-lactic acid that provides the support and a coating of poly-D,L-lactic acid that contains and controls the release of the antiproliferative agent everolimus. We assessed the feasibility and safety of this ... (Read Full Article)

    Comment on Article Mentions:   Hector M. Garcia-Garcia   Patrick W. Serruys   Evelyn Regar

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