Articles from Heart

1. Cardiac Optical Coherence Tomography

   Heart (Aug 13 2008) Cardiology Explore Article

   Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially treat these ... (Read Full Article)
   

   Comment on Article Mentions:   Massachusetts General Hospital   Ik-Kyung Jang   Harvard University

2. In vivo optical coherence tomography of experimental thrombosis in a rabbit carotid model

   Heart (May 13 2008) Cardiology Explore Article

   Background: Plaque rupture with subsequent thrombosis is recognised as the underlying pathophysiology of most acute coronary syndromes. Thus, direct thrombus visualisation in vivo may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of imaging acute thrombosis in vivo using optical coherence tomography (OCT) in an experimental thrombosis animal model. Methods and results: Nine male New Zealand White rabbits (weight 3.0 kg) were made ... (Read Full Article)
   

   Comment on Article Mentions:   LightLab Imaging

3. Identification of multiple plaque ruptures by optical coherence tomography in a patient with acute myocardial infarction: a three-vessel study

   Heart (Apr 13 2008) Cardiology Explore Article

   Optical coherence tomography (OCT) is a new imaging modality capable of obtaining cross-sectional images of coronary vessels with a high resolution of about 10 µm, which is about 10-fold greater than that of intravascular ultrasound. A 57-year-old man was admitted to our hospital with acute posterior myocardial infarction. An emergency coronary angiography demonstrated 99% stenosis (TIMI 2 flow) in segment 11 of the left circumflex artery, and 75% stenosis in ... (Read Full Article)
   

   Comment on Article Mentions:   Lightlab ImageWire

4. Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography

   Heart (Apr 13 2008) Cardiology Explore Article

   Objective: To analyse the neointimal coverage of sirolimus-eluting stent (SES) and bare-metal stent (BMS) visualised in vivo by optical coherence tomography (OCT). Methods: OCT images were obtained in 26 coronary vessels of 24 patients at 5–93 months after SES or BMS deployment. The short-term BMS group (BMS1) consisted of eight BMS in seven patients at 5–10 months of follow-up, the long-term BMS group (BMS2) consisted of six BMS in six ... (Read Full Article)
   

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5. Evaluation of intracoronary stenting by intravascular optical coherence tomography

   Heart (Apr 7 2008) Cardiology Explore Article

   Wellman Laboratories of Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Background: Conventional contrast cineangiography and intravascular ultrasound (IVUS) provide a limited definition of vessel microstructure and are unable to evaluate dissection, tissue prolapse, and stent apposition on a size scale less than 100 µm. Objective: To evaluate the use of intravascular optical coherence tomography (OCT) to assess the coronary arteries in patients undergoing coronary stenting. Methods: ... (Read Full Article)
   

   Comment on Article Mentions:   Massachusetts General Hospital   Guillermo J. Tearney   Brett E. Bouma

6. Suspected coronary artery dissection post-stenting, confirmed by optical coherence tomography

   Heart (Feb 13 2008) Cardiology Explore Article

   Conventional coronary angiography has limitations in detecting stent-related complications. This case highlights this limitation and illustrates how intracoronary imaging with optical coherence tomography helps in this situation. A 60-year-old man with stable angina underwent elective percutaneous coronary intervention to the right coronary artery (panel A). The lesion was directly stented with a 3.0x32 mm paclitaxel-eluting stent (PES) deployed mid-vessel at nominal pressure, and an overlapped 3.0x24 mm proximal PES back ... (Read Full Article)
   

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7. In vivo visualisation of coronary artery development by high-resolution optical coherence tomography

   Heart (Jan 13 2008) Cardiology Explore Article

   Full Text In vivo visualisation of coronary artery development by high-resolution optical... Norozi et al. Heart.2008; 94: 130. Ao, ascending aorta; LA, left atrium; LV, left ventricle; PA, pulmonary artery; RA, right atrium; RB, right brachiocephalic artery arising from the aorta ascendens; RV, right ventricle. Arrow in A shows the interventricular groove. Arrowheads indicate the course of the right coronary artery (RCA); small arrows, aortic valve cusps; star, aortic sinus. ... (Read Full Article)
   

   Comment on Article Mentions:   Technical University of Denmark   Lars Thrane

8. Does optical coherence tomography identify arterial healing after stenting? An in vivo comparison with histology, in a rabbit carotid model

   Heart (Jan 13 2008) Cardiology Explore Article

   Objective: To verify whether optical coherence tomography (OCT) can accurately monitor the occurrence of arterial healing after stenting. Setting: Delayed stent endothelialisation may predispose to stent thrombosis. OCT is a high-resolution intravascular imaging technique that accurately identifies stent struts and arterial tissues. Design and interventions: Eight New Zealand white rabbits underwent the implantation of single bare metal stents (diameter 2–2.5 mm, length 8–13 mm) in the right common carotid artery ... (Read Full Article)
   

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9. In Vivo Optical Coherence Tomography (OCT) of Experimental Thrombosis in a Rabbit Carotid Model

   Heart (Oct 18 2007) Cardiology Explore Article

   Background Plaque rupture with subsequent thrombosis is recognized as the underlying pathophysiology of most acute coronary syndromes. Thus, direct thrombus visualization in vivo may be beneficial for both diagnosis and guidance of therapy. We sought to test the feasibility of imaging acute thrombosis in vivo using OCT, in an experimental thrombosis animal model. Methods and Results Nine male New Zealand White rabbits (weight, ¡Ö3.0 kg) were made atherosclerotic with a ... (Read Full Article)
   

   Comment on Article Mentions:   LightLab Imaging

10. Optical coherence tomography after cutting balloon angioplasty

    Heart (Jun 18 2007) Cardiology Explore Article

    Optical coherence tomography (OCT) is a recently developed optical imaging technique that provides high-resolution (approximately 10–20 µm) cross-sectional images of vessels. A 74-year-old man was admitted for chest pain. A coronary angiogram showed diffuse in-stent restenosis of an Express (Boston Scientific Corporation and Medinol Ltd) 2.75 x 15 mm stent which had been implanted in the left anterior descending coronary artery six months earlier (panel A; arrow). Using OCT (Image ... (Read Full Article)
    

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