Articles from Institute of Physics

1. Multiple interference and spatial frequencies' effect on the application of frequency-domain optical coherence tomography to thin films' metrology

   Institute of Physics (Nov 19 2008) Microscopy , Non-Medical Explore Article

   Abstract. Frequency-domain optical coherence tomography (FD-OCT) was proved to be very useful under two conditions: (i) the layered sample scatters so that multiple interferences do not exist and (ii) the interferometer uses collimated beams so that a single spatial frequency is used. We examine the use of FD-OCT for thin films' metrology when multiple interferences and a range of spatial frequencies exist, such as with interference microscopy where the spatial ... (Read Full Article)
   

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2. An optical coherence tomography (OCT)-based air jet indentation system for measuring the mechanical properties of soft tissues

   Institute of Physics (Nov 19 2008) Explore Article

   Abstract. A novel noncontact indentation system with the combination of an air jet and optical coherence tomography (OCT) was presented in this paper for the quantitative measurement of the mechanical properties of soft tissues. The key idea of this method is to use a pressure-controlled air jet as an indenter to compress the soft tissue in a noncontact way and utilize the OCT signals to extract the deformation induced. This ... (Read Full Article)
   

   Comment on Article Mentions:   University of California at Irvine

3. Optical and terahertz measurement techniques for flat-faced pharmaceutical tablets: a case study of gloss, surface roughness and bulk properties of starch acetate tablets

   Institute of Physics (Nov 11 2008) Non-Medical Explore Article

   Abstract. Surface and bulk properties of flat-faced starch acetate tablets were studied. For surface quality inspection optical coherence tomography and recently developed diffractive glossmeter were utilized. Both these optical devices together provide local information on surface roughness and gloss of a tablet over a measured area. The concepts of mean topography and mean gloss profile for surface quality of a tablet are introduced. It was observed that the surface quality ... (Read Full Article)
   

   Comment on Article Mentions:   University of Oulu   Risto Myllylä

4. Potential ability of hematoporphyrin to enhance an optical coherence tomographic image of gastric cancer in vivo in mice

   Institute of Physics (Nov 6 2008) Explore Article

   Abstract. An ideal diagnostic system for the tumor tissues should be able to detect and define the location of tumor tissues and the early development of malignant diseases. There is great need for enhancement of imaging ability to tumor tissues. Optical coherence tomography (OCT) is used in detection and location of varied tumor tissues. In order to improve the sensitivity and specificity of an OCT image, hematoporphyrin as a new ... (Read Full Article)
   

   Comment on Article Mentions:   Oregon Health & Science University   Ruikang K. Wang

5. Design and development of a 3D scanning Mems Oct probe using a novel SiOB package assembly

   Institute of Physics (Oct 29 2008) Explore Article

   Abstract. A MEMS optical coherence tomography (OCT) probe prototype was developed using a unique assembly based on silicon optical bench (SiOB) methodology. The probe is formed by integrating a three-dimensional (3D) scanning micromirror, gradient refractive index (GRIN) lens and optical fiber on SiOB substrates having prefabricated self-aligned slots. The two-axis scanning micromirror is based on electrothermal actuation with required voltage less than 2 V for mechanical deflections up to 17°. ... (Read Full Article)
   

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6. A model of speckle contrast in optical coherence tomography for characterizing the scattering coefficient of homogenous tissues

   Institute of Physics (Sep 29 2008) Explore Article

   Abstract. We present a theoretical model for analyzing the speckle contrast of optical coherence tomography (OCT). This model is based on the addition of noise and an OCT signal in the logarithmic scale. The theoretical model reveals that, for the superficial layer of homogenous tissue, the contrast ratio is a linear function of the location of the coherence gate in the sample and the slope of this linear dependence is ... (Read Full Article)
   

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7. Changes in wall motion and blood flow in the outflow tract of chick embryonic hearts observed with optical coherence tomography after outflow tract banding and vitelline-vein ligation

   Institute of Physics (Aug 21 2008) Cardiology Explore Article

   Author(s): Sandra Rugonyi, Carley Shaut, Aiping Liu, Kent Thornburg and Ruikang K Wang. Affiliation(s): Division of Biomedical Engineering, Oregon Health & Science University, 3303 SW Bond Ave., CH13B, Portland, OR 97239, USA; Heart Research Center, Oregon Health & Science University, Portland, OR, USA (Read Full Article)
   

   Comment on Article Mentions:   Oregon Health & Science University   Ruikang K. Wang

8. Contrasting properties of gold nanoparticles for optical coherence tomography: phantom, in vivo studies and Monte Carlo simulation

   Institute of Physics (Aug 17 2008) Explore Article

   Author(s): E V Zagaynova, M V Shirmanova, M Yu Kirillin, B N Khlebtsov, A G Orlova, I V Balalaeva, M A Sirotkina, M L Bugrova, P D Agrba and V A KamenskyAffiliation(s): Nizhny Novgorod State Medical Academy, 603005, Minin and Pozharsky square, 10/1, Nizhny Novgorod, Russia; NI Lobachevsky State University of Nizhny Novgorod, 603950 Gagarin Street, 23, Nizhny Novgorod, Russia; Optoelectronics and Measurement Techniques Laboratory, University of Oulu, PO Box ... (Read Full Article)
   

   Comment on Article Mentions:   University of Oulu

9. Deformable and durable phantoms with controlled density of scatterers

   Institute of Physics (Jun 16 2008) Explore Article

   Author(s): Charles-Etienne Bisaillon, Guy Lamouche, Romain Maciejko, Marc Dufour and Jean-Pierre Monchalin. Affiliation(s): Industrial Materials Institute, National Research Council Canada, 75 de Mortagne, Boucherville, Québec J4B 6Y4, Canada; Optoelectronics Laboratory, Engineering Physics, Ecole Polytechnique de Montréal, PO Box 6079, Station 'Centre-ville' Montréal, Québec H3C 3A7, Canada (Read Full Article)
   

   Comment on Article Mentions:   Ecole Polytechnique de Montréal   Romain Maciejko   National Research Council Canada

10. Investigations on laser hard tissue ablation under various environments

    Institute of Physics (Jun 2 2008) Explore Article

    The purpose of this study was to investigate the effect of liquid environments upon laser bone ablation. A long-pulsed Er,Cr:YSGG laser was employed to ablate bovine bone tibia at various radiant exposures under dry, wet (using water or perfluorocarbon) and spray environmental conditions. Energy loss by the application of liquid during laser irradiation was evaluated, and ablation performance for all conditions was quantitatively measured by optical coherence tomography (OCT). Microscope ... (Read Full Article)
    

    Comment on Article Mentions:   University of Texas at Austin   Ashley J. Welch

11. Investigation of polymer and polymer/fibre composite materials with optical coherence tomography

    Institute of Physics (May 22 2008) Non-Medical Explore Article

    Optical coherence tomography (OCT), a technique originally proposed for applications in the field of biomedical diagnostics, is shown to be an efficient measurement technique for a multitude of problems posed in technical engineering and material research. Especially advanced OCT modifications, involving ultrahigh-resolution (UHR) imaging and fast Fourier-domain (FD) techniques, show promising potential, as successfully demonstrated in this paper by a variety of applications from the field of polymer materials. Thin ... (Read Full Article)
    

    Comment on Article Mentions:   Medical University of Vienna   Upper Austrian Research GmbH   Christoph K. Hitzenberger

12. Optical tomography and digital holography

    Institute of Physics (May 22 2008) Explore Article

    Editorial: The articles in this special feature in Measurement Science and Technology concern exciting new developments in the field of digital holography—the process of electronically recording and numerically reconstructing an optical field [1]. Making use of the enormous advances in digital imaging and computer technology, digital holography is presented in a range of applications from fluid flow measurement and structural analysis to medical imaging. (Read Full Article)
    

    Comment on Article Mentions:   David Stifter

13. Holography, tomography and 3D microscopy as linear filtering operations

    Institute of Physics (May 22 2008) Microscopy Explore Article

    In this paper, we characterize 3D optical imaging techniques as 3D linear shift-invariant filtering operations. From the Helmholtz equation that is the basis of scalar diffraction theory, we show that the scattered field, or indeed a holographic reconstruction of this field, can be considered to be the result of a linear filtering operation applied to a source distribution. We note that if the scattering is weak, the source distribution is ... (Read Full Article)
    

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14. An automatic algorithm for detecting stent endothelialization from volumetric optical coherence tomography datasets

    Institute of Physics (May 20 2008) Cardiology Explore Article

    Recent research has suggested that endothelialization of vascular stents is crucial to reducing the risk of late stent thrombosis. With a resolution of approximately 10 µm, optical coherence tomography (OCT) may be an appropriate imaging modality for visualizing the vascular response to a stent and measuring the percentage of struts covered with an anti-thrombogenic cellular lining. We developed an image analysis program to locate covered and uncovered stent struts in ... (Read Full Article)
    

    Comment on Article Mentions:   Jennifer K. Barton

15. Fiber optic tunable probe for endoscopic optical coherence tomography

    Institute of Physics (Apr 2 2008) Endoscopy , Ophthalmology Explore Article

    Khaled Aljasem, Armin Werber, Andreas Seifert and Hans Zappe Abstract. A novel miniaturized fiber optic tunable endoscopic probe based on a pneumatically actuated micro-lens is presented. The probe has a diameter of ~4 mm and is integrated into a time-domain optical coherence tomography (OCT) system. The integration of the tunable lens with the OCT system leads to a uniformly high lateral resolution and high contrast of the OCT images over ... (Read Full Article)
    

    Comment on Article Mentions:   University of Freiburg

16. Fast 3D in vivo swept-source optical coherence tomography using a two-axis MEMS scanning micromirror

    Institute of Physics (Apr 2 2008) Explore Article

    Abstract. We report on a fibre-based forward-imaging swept-source optical coherence tomography system using a high-reflectivity two-axis microelectromechanical scanning mirror for high-speed 3D in vivo visualization of cellular-scale architecture of biological specimens. The scanning micromirrors, based on electrostatic staggered vertical comb drive actuators, can provide ± 9° of optical deflection on both rotation axes and uniform reflectivity of greater than 90% over the range of imaging wavelengths (1260–1360 nm), allowing for ... (Read Full Article)
    

    Comment on Article Mentions:   CardioSpectra   John Zhang   Thomas E. Milner

17. Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography

    Institute of Physics (Jan 8 2008) Non-Medical Explore Article

    Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography 1 Laser Applications and Holography Laboratory, Instrument Design Development Centre, Indian Institute of Technology Delhi, Hauz Khas, New Delhi-110 016, India 2 Institute for Plasma Research, Bhat, Gandhinagar, 382428, India E-mail: dsmehta@iddc.iitd.ac.in Abstract. We demonstrate simultaneous topography and tomography of latent fingerprints using full-field swept-source opti (Read Full Article)
    

    Comment on Article Mentions:   Dalip Singh Mehta   Satish Kumar Dubey   Indian Institute of Technology at Delhi

18. A two axes scanning Soi Mems micromirror for endoscopic bioimaging

    Institute of Physics (Dec 11 2007) Endoscopy Explore Article

    A two axes scanning SOI MEMS micromirror for endoscopic bioimaging 1 A-STAR Institute of Microelectronics, Science Park Road, Singapore 117685 2 Division of Bioengineering, NUS, 21 Lower Kent Ridge Road, Singapore 119077 3 National Cancer Centre, 11 Hospital Drive, Singapore 169610 E-mail: janak@ime.a-star.edu.sg Abstract. A novel silicon on insulator (SOI) MEMS process has been designed and developed to realize a two axes thermally actuated single crystal silicon micromirror device, which ... (Read Full Article)
    

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19. Digital phase stabilization to improve detection sensitivity for optical coherence tomography

    Institute of Physics (Dec 9 2007) Explore Article

    Optical coherence tomography has become an important tool for medical imaging and increasingly for quantitative metrological applications. As a consequence detection sensitivity is highly valued. In this paper, we introduce a novel post-processing technique for digitally stabilizing and spectrally averaging optical coherence tomography datasets in order to enhance detection sensitivity. We demonstrate sensitivity gains of 18 dB when the algorithm is applied to data from a high-speed Fourier domain system. (Read Full Article)
    

    Comment on Article Mentions:   National Physical Laboratory   Oregon Health & Science University   Pete H. Tomlins

20. Hard tissue ablation with a spray-assisted mid-IR laser

    Institute of Physics (Nov 23 2007) Explore Article

    1 American Medical Systems, Minnetonka, MN, USA 2 Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA 3 BioLase Technology, Irvine, CA, USA E-mail: wookiedokie@gmail.com Abstract. The objective of this study was to understand the dominant mechanism(s) for dental enamel ablation with the application of water spray. A free-running Er,Cr:YSGG (yttrium, scandium, gallium, garnet) laser was used to ablate human e (Read Full Article)
    

    Comment on Article Mentions:   University of Texas at Austin

21. Robust intravascular optical coherence elastography by line correlations

    Institute of Physics (May 7 2007) Cardiology Explore Article

    Abstract. We present a new method for intravascular optical coherence elastography, which is robust against motion artefacts. It employs the correlation between adjacent lines, instead of subsequent frames. Pressure to deform the tissue is applied synchronously with the line scan rate of the optical coherence tomography (OCT) instrument. The viability of the method is demonstrated with a simulation study. We find that the root mean square (rms) error of the ... (Read Full Article)
    

    Comment on Article Mentions:   Thoraxcenter at Erasmus University Medical Center   Gijs van Soest   Anton F. W. van der Steen

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